Research And Development Scientist

About the jobSenior Research Scientist : Synthesis R&DPurpose of the Role:To contribute to early-stage drug discovery programs by designing and synthesizing novel small molecules that meet client objectives. The role supports hit-to-lead and lead optimization efforts through data-driven medicinal chemistry strategies, with the goal of delivering high-quality drug candidates in a collaborative CRO environment.Key Responsibilities:Strategic & Scientific:Design and synthesize novel chemical entities (NCEs) guided by SAR and target profile.Contribute to lead identification and optimization in FTE or integrated drug discovery (IDD) projects.Collaborate with cross-functional teams (e.g., biology, ADME, computational chemistry) to advance candidate selection.Analyze biological and ADME data to refine compound design strategies.Operational:Plan and execute multistep organic syntheses with minimal supervision.Characterize compounds using NMR, LCMS, HPLC, and other analytical tools.Maintain detailed and accurate experimental records (ELN/lab notebooks).Deliver high-purity compounds on time to meet client/project goals.Collaboration & Communication:Actively participate in team meetings, project reviews, and client discussions.Coordinate with analytical and biology teams for data turnaround and integration.Present experimental results and SAR insights to internal and external stakeholders.Compliance & Documentation:Follow lab safety protocols and maintain GLP/GMP (where applicable).Ensure adherence to SOPs and maintain project documentation for IP protection and client reporting.Qualification & Experience:M.Sc. with 3–8 years of relevant experience in a CRO environment.Proven expertise in synthetic organic chemistry and medicinal chemistry principles.Experience in client-facing discovery projects is strongly preferred.Key Skills & Competencies:Deep understanding of SAR, pharmacophores, and drug-likeness criteria.Strong skills in synthetic planning, reaction optimization, and troubleshooting.Excellent communication and data presentation abilities.Ability to multitask and work effectively in a high-paced, collaborative environment.

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