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Job Title:

Senior Bioinformatician

Company: bigtec Private Limited

Location: Guntur, Andhra Pradesh

Created: 2026-01-11

Job Type: Full Time

Job Description:

We’re seeking aSenior Bioinformaticianto lead bioinformatics strategy and decision-making across theentire assay lifecycle —from in-silico design and design verification to validation and post-market genomic surveillance.In this role, you’ll ensure assay targets, primers, probes, and controls arescientifically robust, regulatory-compliant, and future-proofacross qRT-PCR, multiplex, isothermal, immuno-based, and Point-of-Care diagnostic platforms. Key Responsibilities Lead in-silico design and verification of molecular and PoC assays Design and evaluate targets, primers, probes, internal/process controls, and reference sequences Perform inclusivity/exclusivity, variant, mutation, and cross-reactivity analyses Assess target conservation, multiplex compatibility, mismatch tolerance, and secondary structure risks Define bioinformatics acceptance criteria aligned withMIQE 2.0, CLSI, ISO 13485 & ISO 14971 Support DOE-based optimization, risk management, and design change impact assessments Contribute to validation readiness (LoD, robustness, interference studies) Monitor global genomic datasets to supportpost-market surveillanceand ongoing assay performance Qualifications M.Sc./M.Tech/Ph.D. in Bioinformatics, Genomics, Computational Biology, Biotechnology, or related field 3–7 yearsof industry experience in bioinformatics-driven assay design, validation, or genomic surveillance Experience working inregulated IVD environments Strong cross-functional communication skills and regulatory mindset

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